Gene regulation / a eukaryotic perspective / David S. Latchman.
Material type:
TextSeries: Advanced text: Publisher: New York : Taylor & Francis, 2005Edition: 5th edDescription: x, 374 pages : illustrations (some color) ; 25 cmISBN: 0415365104; 9780415365109Subject(s): Genetic regulation | Gene expression | Eukaryotic cells | Genetic transcription | Gene Expression Regulation
| Transcription, Genetic | Eukaryotic Cells | Gene Expression | Regulation genetique | Expression genique | Cellules eucaryotes | Transcription genetique | Eukaryotic cells | Gene expression | Genetic regulation | Genetic transcription | Genregulation | Regulacao genica | Expressao genica | Transcricao genica | Celulas eucarioticasGenre/Form: Internet resource.DDC classification: 574.87328 LOC classification: QH450.2 | .L37 2005Other classification: BIO 180f | BIO 220f | BIO 450f | BIO 750f | WG 1940 | QU 475 Online resources: Table of contents | Table of contents | Table of contents | Table of contents | Publisher description | Item type | Current location | Call number | Status | Date due | Barcode |
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GKVK Library | 574.87328 LAT (Browse shelf) | Available | STB-357 |
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| 574.87328 AUS Genome Mathematics : Two methods of analysing proteins and nucleic acid molecules using boolean algebra / | 574.87328 BHA Molecular genetics | 574.87328 GRA Molecular and genome evolution / | 574.87328 LAT Gene regulation / | 574.87328015 NIE Statistical methods in molecular evolution / | 574.873282 ALC DNA Technology: | 574.873282 ALC DNA Technology: |
Includes bibliographical references and index.
Tissue-specific expression of proteins and messenger RNAs -- The DNA of different cell types is similar in both amount and type -- Gene expression -- Regulation at transcription -- Post-transcriptional regulation -- Transcriptional control : chromatin structure -- Transcriptional control : DNA sequence elements -- Transcriptional control : transcription factors -- Gene regulation and human disease.
Provides the student with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview. For this fifth edition, in addition to extensive updating of existing material, sections on large-scale methodologies have been expanded, and a new section included on regulation by small interfering RNAs. More detail has been added on the role of multi-protein complexes in transcriptional activation and the discussion of the regulation of transcription factor activity by specific modifications to include acetylation and ubiquitination as well as phosphorylation. The final chapter on gene regulation and human disease now includes additional novel examples, such as RNA edition in motor neurone disease, role of the transcriptional co-activator CBP in Alzheimer's disease and PML-RAR involvement in acute promyelocytic leukemia.
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