TY - BOOK AU - Primrose,S.B. AU - Twyman,Richard M. AU - Primrose,S.B. AU - Primrose,S.B. TI - Principles of gene manipulation and genomics SN - 1405135441 AV - QH442 .O42 2006 U1 - 575.12 22 PY - 2006/// CY - Malden, MA, Oxford PB - Blackwell Pub. KW - Genetic engineering KW - Genomics KW - Gene mapping KW - Nucleotide sequence KW - Recombinant DNA KW - Proteomics KW - Genetic Engineering KW - DNA, Recombinant KW - Chromosome Mapping KW - Base Sequence KW - Manipulations genetiques KW - Genomique KW - Proteomique KW - ADN recombinant KW - Cartes chromosomiques KW - Genie genetique KW - fast KW - Genanalyse KW - gnd KW - Gentechnologie KW - Internet resource N1 - Revised edition of: Principles of gene manipulation. 6th ed. 2001 and Principles of genome analysis and genomics / Sandy B. Primrose, Richard M. Twyman. 3rd ed. 2003; Includes bibliographical references (pages 547-626) and index; Gene manipulation in the post-genomics era -- Basic techniques -- Cutting and joining DNA molecules -- Basic biology of plasmid and phage vectors -- Cosmids, phasmids, and other advanced vectors -- Gene cloning strategies -- Sequencing genes and short stretches of DNA -- Changing genes : site-directed mutagenesis and protein engineering -- Bioinformatics -- Cloning in bacteria other than Escherichia coli -- Cloning in Saccharomyces cerevisiaea and other fungi -- Gene transfer to animal cells -- Genetic manipulation of animals -- Gene transfer to plants -- Advanced transgenic technology -- The organization and structure of genomes -- Mapping and sequencing genomes -- Comparative genomics -- Large-scale mutagenesis and interference -- Analysis of the transcriptome -- Proteomics I : expression analysis and characterization of proteins -- Proteomics II : analysis of protein structures -- Proteomics III : protein interactions -- Metabolomics and global biochemical networks -- Applications of genomics : understanding the basis of polygenic disorders and identifying quantitative trait loci -- Applications of recombinant DNA technology N2 - "The increasing integration between gene manipulation and genomics is embraced in this book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books, Principles of Gene Manipulation and Principles of Genomic Analysis and Genomics. This new text has been comprehensively revived, updated, and rewritten to encompass within one volume, basic and advanced gene-manipulation techniques, genome analysis, genomics, transcriptomics, proteomics, and metabolomics, as well as the applications of these fascinating technologies."; "Principles of Gene Manipulation and Genomics is an accessible and up-to-date guide to this exciting field, and is the essential reference for upper-level undergraduate and graduate students of genetics, genomics, molecular biology, and recombinant DNA technology."--Jacket UR - http://catdir.loc.gov/catdir/toc/ecip0515/2005018202.html UR - http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014181074&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA UR - http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014181074&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA UR - http://catdir.loc.gov/catdir/toc/ecip0619/2006026294.html UR - http://www.dawsonera.com/depp/reader/protected/external/AbstractView/S9781444309096 UR - http://catdir.loc.gov/catdir/enhancements/fy0802/2006026294-b.html UR - http://lib.leeds.ac.uk/record=b2646534 ER -